Biocatalysis refers to the process of chemical conversion using enzymes or biological organisms (cells, organelles, tissues, etc.) as a catalyst. This reaction process is also called biotransformation.

The organisms commonly used in biocatalysis are mainly microorganisms, and their essence is to catalyze the enzymes in the microbial cells to promote the process of biotransformation.

advantage

The action conditions are mild, and are basically completed in an environment such as normal temperature, neutrality, and water;

Unique and efficient substrate selectivity (because the enzymes in the catalytic process are specific, ie one enzyme can only catalyze the reaction of a specific substrate, but one substrate may be catalyzed by multiple enzymes) );

The synthesis of chiral active pharmaceutical ingredients has unique advantages.

Disadvantage

Biocatalysts are often unstable in the reaction medium;

There are too few biocatalysts currently available for industrial applications;

The biocatalyst development cycle is longer.